Updated on 2026/04/30

写真a

 
WADAZUMI Tsuyoshi
 
Organization
Faculty of Health and Well-being Professor
Title
Professor
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Degree

  • 博士（学術） ( 2000.3 )

Research Areas

  • Life Science / Sports sciences

Education

  • Osaka City University   Graduate School, Division of Domestic Science

    2000

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  • Nippon Sport Science University   Faculty of Physical Education

    - 1984

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  • Nippon Sport Science University   Graduate School, Division of Physical Recreation

    1986

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  • Osaka City University   Graduate School, Division of Domestic Science

    2000

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Professional Memberships

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Committee Memberships

  •   評議委員;体力医学会近畿地方会幹事  

    2018.4   

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  •   体力医学会近畿地方会幹事  

    2018.4   

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  • 日本体力医学会   評議委員  

    2018.4   

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Papers

  • Carbohydrate mouth rinse during physical activity to improve cognitive function: A randomized cross-over trial. Reviewed

    Donghyun KIM, Tsuyoshi WADAZUMI

    The Journal of Physical Fitness and Sports Medicine.   15 ( 2 )   2026.3

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    Authorship：Last author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

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  • Effects of Paprika Xanthophyll Intake on Endurance and Cognitive Function in College Students: A Crossover Randomized Controlled Trial Reviewed

    Donghyun Kim, Tsuyoshi Wadazumi

    Nutrients   17 ( 17 )   2780 - 2780   2025.8

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    Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

    Background/Objective: Paprika xanthophylls (PXs) have potent antioxidant properties and are believed to improve oxygen delivery (DO2) efficiency by enhancing red blood cell (RBC) deformability. This study investigated whether PX ingestion improves endurance performance and subsequently enhances cognitive function by improving brain microcirculation. Methods: A crossover design was used to compare the effects of PX ingestion and a control condition in 21 healthy college students (18 males, 3 females). Each participant served as their own control, completing both conditions in a randomized order with a one-month washout period to eliminate any carryover effects. The participants underwent an incremental load test, a constant load test, the Trail Making Test Type B (TMT-B), and the Stroop test (ST). Results: In the incremental tests, the PX group showed a significantly lower heart rate (p = 0.032) and higher exercise efficiency (EE) (p = 0.004). In the constant load test, heart rate was lower (p = 0.020), and EE was higher (p = 0.030). No significant between-group differences were found in the cognitive tests; however, the PX group showed significant improvements in the TMT-B (p = 0.034) and ST interference rate I (p = 0.040). Conclusions: It is speculated that PX intake may improve DO2 efficiency, which could contribute to the observed enhancements in endurance performance and, in turn, positively affect cognitive function by optimizing the brain’s oxygenation state. However, due to the absence of a placebo control group and unmeasured RBC deformability and cerebral blood flow, as well as a significant male predominance, this study’s results should be interpreted with caution.

    File： nutrients-17-02780.pdf

    DOI： 10.3390/nu17172780

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  • Effects of Trehalose Solutions at Different Concentrations on High-Intensity Intermittent Exercise Performance Reviewed

    Nutrients   2022, 14(9), 1776   2022.4

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    Trehalose solution ingested during exercise induces gradual increases in blood glucose levels and the insulin response compared with glucose solution. Trehalose solution aids in the maintenance of performance in the later stages of prolonged exercise. The purpose of this study was to identify the lowest concentration at which the properties of trehalose could be exploited. Groups of 12 healthy men (21.3 ± 1.3 years) and 10 healthy men (21.1 ± 0.7 years) with recreational training were included in experiments 1 and 2, respectively. Both experiments followed the same protocol. After fasting for 12 h, the participants performed a 60 min constant-load exercise at 40% V˙O2 peak using a bicycle ergometer and ingested 500 mL of a trial drink (experiment 1: water, 8% glucose, and 6 or 8% trehalose; experiment 2: 4 or 6% trehalose). They performed four sets of the Wingate test combined with a 30 min constant-load exercise at 40% V˙O2 peak. The experiment was conducted using a randomized cross-over design; trial drink experiments were conducted over intervals of 7 to 12 days. The exercise performance was evaluated based on mean power in the Wingate test. Blood was collected from the fingertip at 12 points during each experiment to measure blood glucose levels. During the high-intensity 5 h intermittent exercise, no differences were found between the groups in exercise performance in the later stages with concentrations of 8, 6, and 4% trehalose solution. The results suggest that trehalose could be useful for making a new type of mixed carbohydrate solution. Further studies to determine the trehalose response of individual athletes during endurance exercise are needed.

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  • Carbohydrate Mouth Rinse and Spray Improve Prolonged Exercise Performance in Recreationally Trained Male College Students Reviewed

    Asako Shirai, Tsuyoshi Wadazumi, Yoko Hirata, Naomi Hamada, Nobuko Hongu

    Sports   Sports 2022, 10(4), 51   2022.3

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    Mouth rinsing with a carbohydrate (CHO) solution has emerged as a sports nutrition strategy to increase endurance performance. This study aimed to clarify the effects of two forms of CHO sensing in the mouth (i.e., CHO mouth rinse (CMR) and CHO mouth spray (CMS)) on exercise performance during prolonged exercise, including ultra-high intensity intermittent exercise over time. We conducted the following experimental trials: (1) 6% glucose solution (G), (2) 6% CMR, (3) 6% CMS, and (4) water (WAT). These trials were conducted at least 1 week apart in a randomized crossover design. Eight male college students performed constant-load exercise for 60 min (intensity 40% VO2peak), four sets of the Wingate test (three 30 s Wingate tests with a 4 min recovery between each test), and a constant-load exercise for 30 min (intensity 40% VO2peak). The mean exercise power output (Watt), ratings of perceived exertion, and blood glucose levels were measured. We found that the mean power values of the CMR and CMS in the third and fourth sets was significantly higher than that of WAT (p < 0.05), and that the G trial did not show a significant difference from any other trial. Thus, when compared to G or WAT, CMR and CMS can help improve endurance exercise performance.

    DOI： 10.3390/sports10040051

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  • Effect of Paprika Xanthophyll Supplementation on Cognitive Improvement in a Multitasking Exercise: A Pilot Study for Middle-Aged and Older Adults Reviewed

    Asako Shirai, Tsuyoshi Wadazumi

    Healthcare   2022, 10(1), 81   2022.1

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    Ingestion of paprika xanthophyll supplement (PX), which has antioxidant effects, has been recently reported to maintain red blood cell deformability and improve oxygen delivery efficiency. Therefore, we hypothesized that the brain activation induced by multitasking exercise in middle-aged and older participants along with the improved erythrocyte oxygen-carrying efficiency induced by PX supplementation would show a synergistic effect, increasing oxygen supply to the brain and improving cognitive function more effectively. In study 1, cerebral blood flow measurements were conducted during the multitasking exercise and cognitive function tests to verify their effect on cognitive function. The results confirmed that cerebral blood flow increased during the exercise and cognitive function improved after the exercise. In study 2, we compared the effects of the multitasking exercise on cognitive function before and after PX supplementation in middle-aged and older participants to evaluate the effects of PX supplementation. The results suggested that PX supplementation enhanced the effects of active multitasking exercise on cognitive function. We speculate that the improvement of oxygen transport efficiency by PX resulted in more effective oxygen supply, allowing the multitasking exercise to occur more effectively, which was reflected as an improvement in the cognitive function.

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  • The effect of carbohydrate mouth rinse in isometric hand grip performance Reviewed

    Yoko Hirata, Tsuyoshi Wadazumi, Naomi Hamada, Asako Shirai, Hitoshi Watanabe

    Japanese Journal of Physical Fitness and Sports Medicine   70 ( 4 )   269 - 276   2021.8

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Physical Fitness and Sports Medicine  

    DOI： 10.7600/jspfsm.70.269

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  • Single Ingestion of Trehalose Enhances Prolonged Exercise Performance by Effective Use of Glucose and Lipid in Healthy Men Reviewed

    Naomi Hamada, Tsuyoshi Wadazumi, Yoko Hirata, Mayumi Kuriyama, Kanji Watanabe, Hitoshi Watanabe, Nobuko Hongu, Norie Arai

    2021, 13(5), 1439; https://doi.org/10.3390/nu13051439   2021.4

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    A single ingestion of trehalose helped to maintain prolonged exercise performance.

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  • Effects of a Single Ingestion of Trehalose during Prolonged Exercise Reviewed

    WADAZUMI,Tsuyoshi

    Sports — Open Access Journal   Sports 2019, 7(5), 100; https://www.mdpi.com/2075-4663/7/5/100   2019.4

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    The aim of this study was twofold. First, we examined exercise performance following ingestions of either GLU, TRE, or water (WAT). The second purpose was to investigate the effects of TRE energy metabolism during prolonged exercise. In conclusion, we provide novel data that a single TRE ingestion was effective in improving prolonged exercise performance by effective use of glucose and lipids.

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  • Detection of metabolic threshold using near-infrared spectroscopy on the incremental handgrip exercise

    WADAZUMI,Tsuyoshi

    Japanese Jouurnal of Hearth, Fitness and Nurtrition   Vol.18, 1(1-5頁)   2013.12

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  • The "IKIGAI" of the elderly women according to household composition Reviewed

    WADAZUMI,Tsuyoshi

    Mukogawa journal of health and exercise science   Vol.3, 1(45-52頁)   2012.12

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  • Influence of carbohydrate fluid intake on high-intensity intermittent exercise performance Reviewed

    WADAZUMI,Tsuyoshi

    Mukogawa journal of health and exercise science   Vol.3, 1(1-11頁) ( 1 )   1 - 11   2012.12

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  • Effect of exercise intensity on mild rhythmic-handgrip-exercise-induced functional sympatholysis

    Hitoshi Watanabe, Kanji Watanabe, Tsuyoshi Wadazumi, Fujiko Yoneyama

    Journal of Physiological Anthropology   26 ( 6 )   593 - 597   2007

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.2114/jpa2.26.593

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  • ．Exercise Intensity during a 30-minute Ground Stroke Rally using Short-tennis Racket and Ball: Comparison Reviewed

    WADAZUMI,Tsuyoshi

    J. Educ. Health Sci   Vol.4, 1(1-9頁)   2006.6

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  • 定常負荷運動開始時の近赤外線分光法による筋内酸素動態の検討 VO2時定数及び無酸素性作業閾値との関係

    三村 達也, 石原 一成, 田中 繁宏, 藤本 繁夫, 弘原海 剛, 宮本 忠吉

    関西臨床スポーツ医・科学研究会誌   10   41 - 42   2001.2

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    Language：Japanese   Publisher：関西臨床スポーツ医・科学研究会  

    運動開始直後の筋内酸素化レベルの低下の程度は,活動筋の酸素利用能と関係があることが示唆された.このレベルが低いほど運動開始時に組織へ酸素を取り込む能力が高く,好気的運動能力の増大につながったと考えられた

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  • Relationships between ADL, QOL and Physical Functions in Elderly Female Residents of Geriatric Health Services Facility.

    ISHIHARA KAZUNARI, MIMURA TATSUYA, WADAZUMI TSUYOSHI, NISHIMOTO KATSUO, TANAKA SHIGEHIRO, FUJIMOTO SHIGEO

    Journal of exercise physiology   16 ( 4 )   179 - 185   2001

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    Language：Japanese   Publisher：The Society of Physical Therapy Science  

    The purpose of this study was to investigate the relationships between activities of daily living (ADL), quality of life (QOL) and physical function in 24 female residents(average age; 81.3±3.8) of geriatric health services facility. The results showed that ADL significantly correlated with walking ability, lower limb function, muscular strength and endurance, and that balance function significantly correlated to walking ability, lower and upper limb function and flexibility. In addition, QOL had relations to both ADL and depression. It is be suggested that QOL reflected not only ADL but also mental factor such as depression. These findings might give an a available information to provide and to develop exercise program for elderly female in geriatric health services facilities.

    DOI： 10.1589/rika.16.179

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  • 高酸素及び低酸素吸入下のランプ負荷運動に伴う下肢筋内酸素濃度動態の解析の試み

    弘原海 剛, 田中 繁宏, 大島 秀武, 藤本 繁夫, 宮本 忠吉, 木村 穣

    関西臨床スポーツ医・科学研究会誌   8   23 - 25   1999.2

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    Language：Japanese   Publisher：関西臨床スポーツ医・科学研究会  

    ランプ負荷運動中における筋内酸素動態に生じる低下反応(NIRS slope)と屈曲点(NT2)を用いて,吸入気ガス濃度(標準ガス,16%O2,40%O2濃度の酸素)の差が酸素動態に及ぼす影響について検討した.活動筋内のNIRS slopeは吸入気ガス濃度の影響を受けないが,酸素交換率の限界(NT2)に達する迄の時間は,低酸素吸入により早められることが明らかになった

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  • Effects of endurance training above the anaerobic threshold on isocapnic buffering phase during incremental exercise in middle-distance runners Reviewed

    Y Oshima, S Tanaka, T Miyamoto, T Wadazumi, N Kurihara, S Fujimoto

    JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE   47 ( 1 )   43 - 51   1998.2

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    Language：English   Publishing type：Research paper (scientific journal)  

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  • Relationships between oxygen uptake kinetics on recovery from maximal exercise and blood lactate, glucose and alanine metabolism Reviewed

    Y Oshima, S Tanaka, T Miyamoto, T Wadazumi, N Kurihara, S Fujimoto

    JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE   46 ( 5 )   479 - 488   1997.10

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

    Web of Science

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  • 近赤外分光法(NIRS)からみた筋肉内酸素動態に及ぼす有酸素トレーニングの影響

    弘原海 剛, 大島 秀武, 宮本 忠吉

    関西臨床スポーツ医・科学研究会誌   6   57 - 59   1997.1

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    Language：Japanese   Publisher：関西臨床スポーツ医・科学研究会  

    ランプ負荷法による自転車運動中において,近赤外分光法により測定された筋肉内酸素濃度の第2屈曲点(NT2)出現の遅延は,トレーニング効果によるものと推察された.このことは,従来よりトレーニング効果の指標として利用されているVO2max, VT, LTに加えNT2が一指標となり得る可能性が示唆された

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  • 定常負荷運動後のVO2及びVCO2回復曲線の検討

    宮本 忠吉, 大島 秀武, 弘原海 剛

    関西臨床スポーツ医・科学研究会誌   6   53 - 55   1997.1

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    Language：Japanese   Publisher：関西臨床スポーツ医・科学研究会  

    定常負荷運動後におけるVO2の回復曲線の時定数は,運動能力を表わす指標になり得る可能性が示唆された.一方,VCO2の回復曲線に関しては,負荷量や回復時間を考慮して再検討を行う必要性が示された

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Books

  • Block Exercise: A Rhythm-Based Exercise for Enhancing Cognitive Function

    （ Role： Sole author）

    2026.3  （ ISBN:9784873548159 ）

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    Total pages：128p   Language：Japanese  

    CiNii Books

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  • まずはこれだけストレッチ

    弘原海 剛（ Role： Sole author）

    遊タイム出版  2008.7 

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MISC

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Presentations

  • デュアルタスク運動とマウスリンス及びパプリカキサントフィル摂取の併用が深夜の認知機能に及ぼす影響

    金東鉉, 弘原海 剛

    第76回日本体力医学会 オンライン開催  2021 

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    Event date： 2022.9

    Language：Japanese  

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  • Effects of eye movements on cognitive function

    Yamashiro Kaito, Kim Donghyun, Wadazumi Tsuyoshi

    The 76th Japanese Society of Physical Fitness and Sports Medicine  2021.9 

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    Event date： 2021.9

    Language：Japanese  

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  • Effects of dual-task exercise combined with mouth rinse and paprika xanthophyll on cognitive function

    Kim Donghyun, Yamashiro Kaito, Wadazumi Tsuyoshi

    2021.9 

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    Event date： 2021.9

    Language：Japanese  

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  • The effect characteristics of carbohydrate mouth rinse on exercise performance

    WADAZUMI,Tsuyoshi

    The Jouurnal of Physical Fitness and Sports Medicine  2017.12 

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    Event date： 2017.12

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  • Mechanism of the influence of trehalose ingestion on exercise performance

    WADAZUMI,Tsuyoshi

    The Jouurnal of Physical Fitness and Sports Medicine  2016.12 

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    Event date： 2016.12

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  • Influence of different specification in mouth rinse on exercise performance

    WADAZUMI,Tsuyoshi

    The Jouurnal of Physical Fitness and Sports Medicine  2016.12 

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    Event date： 2016.12

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  • パプリカキサントフィル摂取が持久性パフォーマンスおよび認知機能に及ぼす影響―持久力向上状態における認知機能変化に着目して―（クロスオーバーランダム化比較試験）

    金東鉉, 弘原海 剛

    第79回日本体力医学会  2025.9 

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    Language：Japanese   Presentation type：Oral presentation (general)  

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  • パプリカキサントフィルの摂取が生体に及ぼす影響

    金東鉉, 弘原海 剛

    第78回日本体力医学会  2024.9 

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    Language：Japanese   Presentation type：Poster presentation  

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Works

  • Relationship of Tissue Oxygenation Kinetics with Blood Lactate Levels and Integrated Electromyogram Values during Incremental Handgrip Exercise

    2003

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  • Significance of decrease in the muscle oxygenation curve by Near-Infrared-Spectroscopy(NIRS)during RAMP Exercise.

    1998

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  • Influence of Exercise on Audibility

    1992 - 1993

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Research Projects

  • Carbohydrate intake strategy for para-athletes with spinal cord injury during sports activities

    Grant number：22K11529  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）

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  • 高齢者の健康に関する研究

    2003

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    Grant type：Competitive

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  • 運動中の筋内酸素濃度変化について

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    Grant type：Competitive

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  • Basic Research on the Appropriate Level for "Nutrition, Exercise and Rest"

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    Grant type：Competitive

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  • 「栄養・運動・休養」それぞれの至適レベルについての基礎的研究

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    Grant type：Competitive

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  • Change the Oxygenation in muscle during exercise

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    Grant type：Competitive

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Social Activities

  • R & D and dissemination activities of Sakai City version of preventive care exercise "Sakai Co-kara Exercise"

    2014.4 - 2022

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  • 神戸市西区保健福祉部健康福祉課リーダー研修会講師

    2006.4 - 2011

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Devising educational methods

  • ・週1回1コマ分をオフィスアワーとして、学生からの質問や相談に応じている。

Teaching materials

  • ・「現代にとって健康とはなにか」竹内　洋監修、朱鷺書房（2011年）、分担執筆として第3部第5章「健康づくりのための適度な運動とは」を執筆。

Teaching method presentations

  • 　特になし

Special notes on other educational activities

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